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Calming Seborrheic Serum
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Calming Seborrheic Serum
Calming Seborrheic Serum
  • Load image into Gallery viewer, Calming Seborrheic Serum
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Calming Seborrheic Serum
  • Load image into Gallery viewer, Calming Seborrheic Serum

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.5
Rated 4.5 out of 5 stars
1,613 Reviews

Soothe your scalp and face. This all-in-one serum helps disrupt the biofilm, clears away signs of fungus, and calms your skin naturally.

  1. Helps reduce and relieve signs of:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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FEATURED TESTIMONIAL
FEATURED TESTIMONIAL

Lecrae

/

Grammy Winner and Recording Artist

As a public figure with a moody scalp

this product has been a true game-changer for me. Dermazen has(See full testimonial)"

Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Dermazen Calming Seborrheic Serum and Scalp Therapy Shampoo
A third-party clinical trial put Dermazen to the test — and the results speak for themselves.
92%
Flake-Free, Calm Scalp*

Over 92% of all participants in the study reported less dandruff, flakiness, and irritation.*

100%
Increase In Scalp Comfort*

Participants reported feeling more than twice as soothed and calm on their scalp after using Dermazen daily.*

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you'll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like tea tree, MSM (organic sulfur), sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, niacinamide (vitamin B3), urea, and sodium hyaluronate (aka hyaluronic acid) bring the peace you're looking for.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to people struggling with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

Aloe Leaf Juice

Helps soothe irritated scalp and signs of irritation

Xylitol

Works to naturally disrupt the biofilm layer and reduce signs of fungus

Grapefruit Seed Extract

Helps to calm moody scalps and support healthy hair and skin

Tea Tree Essential Oil

Helps calm and reduce signs of inflammation and fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.5
Rated 4.5 out of 5 stars
Based on 1,613 reviews
Total 5 star reviews: 1.2k Total 4 star reviews: 196 Total 3 star reviews: 80 Total 2 star reviews: 39 Total 1 star reviews: 64
89%would recommend this product
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1,613 reviews
  • L
    LaToya
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    5 Stars

    So far, so good!

  • RW
    Rhoan W.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Health
    How old are you? 35-44
    What is your gender? Male
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    5 days ago
    Works great!

    Did not expect this product to work as anything else that I have ever tried worked for maybe a couple of weeks and then nothing. It’s been 3 months now and no sign of issues!

    D Profile picture for Dermazen
    Dermazen
    5 days ago

    THAT MOMENT WHEN someone finally finds the product that actually delivers lasting results instead of just temporary relief? That's everything!

    Three months of clear, comfortable skin after trying so many products that only worked for a couple weeks? That's true relief! We're just happy for you!

    Your skin is clearly loving that consistent, long-term support instead of those short-lived fixes. That kind of sustained improvement is exactly what shows us this formula is working with your skin's natural processes to create real, lasting change.

    Thank you for this amazing 5-star review and for giving the Calming Seborrheic Serum a chance to prove what's possible! 💚

  • CR Profile picture for Craig R.
    Craig R.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 45-54
    What is your gender? Male
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    1 week ago
    After a 25 year battle with dandruff…

    …it’s over! I cannot praise this product enough. It’s been a battle over a quarter century in the making using all the wrong products to get rid of dandruff and Dermazen’s Seborrheic Serum did what the other’s simply couldn’t. After about 9 days of daily use I did the dandruff test and not a single flake fell out. I was gobsmacked. Thank you Dermazen! You got a customer for life!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Now that's 25 YEARS of battling dandruff and now it's finally OVER - what an absolutely incredible victory! 🙌 We're just here completely slack-jawed that after more than a quarter century of trying everything and getting nowhere, just 9 days with the Calming Seborrheic Serum gave you that long-awaited relief!

    The "dandruff test" with not a single flake falling out after all those years of struggle - we can only imagine how gobsmacked and relieved you must have felt in that moment!

    Your scalp is probably feeling more comfortable and confident than it has in years, and you can finally stop worrying about those flakes after 25 years of constant battle. That kind of transformation after such a long journey is everything we could hope for with this serum.

    Thank you for this incredible 5-star review and for sharing your powerful story with us. Having you as a customer for life means the world to us, and stories like yours remind us exactly why we created this serum in the first place. 💚

  • MH
    Marvin H.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face, Ears
    What did this product help with? Flakes, Itching, Build-Up, Skin Tone
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    2 weeks ago
    AMAZING

    I am 7 years into my Loc journey and I have tried so many different oils and products for Seborrheic dermatitis. Nothing worked, until NOW!! This product has worked very good.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Marvin, 7 YEARS of trying everything and nothing working until now - does it feel like you can breathe more freely?! 🙌 Your Loc journey has been such a long one, and we can only imagine how frustrating it must have been to try oil after oil, product after product, without getting the relief your scalp deserved.

    The fact that the Calming Seborrheic Serum finally gave you that "AMAZING" result after all this time shows just how much your scalp was craving the right kind of targeted care all along. Seven years of searching and experimenting, and now you finally have something that actually works -truly awe insp!

    Your locs are probably feeling more comfortable and healthy than they have in years, and you can finally focus on enjoying your hair journey without constantly battling seborrheic dermatitis. That kind of relief after such a long struggle is everything we could hope for with this serum.

    Thank you for this fantastic 5-star review and for not giving up on finding the right solution. Stories like yours remind us exactly why we created this serum in the first place. 💚

  • LB
    Lisa B.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face
    What did this product help with? Flakes, Skin Health, Build-Up
    How old are you? 55-64
    What is your gender? Female
    What texture is your hair? Curly
    Rated 4 out of 5 stars
    2 weeks ago
    It's OK

    I've been using this for over three weeks. So far, there's been some moderate improvement on my face. The areas along my hairline have shown no improvement, as well as some prominent spots under my chin. I'm hoping the areas with no change merely need more time with the product and they'll improve too.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Thanks for sharing your experience with our Calming Seborrheic Serum, Lisa! It's great to hear that you're seeing moderate improvement on your face after three weeks—that's definitely progress in the right direction! We totally understand that some areas can be more stubborn than others, especially along the hairline and under the chin where seborrheic dermatitis can be particularly persistent. You're absolutely right that those areas might just need a bit more time and consistency with the product to see the results. Every person's skin responds at its own pace, so we're hopeful that with continued use you'll start seeing improvement in those trickier spots too! Thanks for the 4 stars and for sticking with your routine! 💚🤩

  • KB
    Kimba B.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Build-Up
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Textured
    Rated 4 out of 5 stars
    2 weeks ago
    Hopeful!

    We are about a month into using derma zen Calming Seborrheic Serum and honestly what I love most is not using prescription chemicals on my daughter’s scalp for her build up issues. We saw great improvement the first week but seem to be almost back to where we started now. I use the product on her build up areas every day and am remaining hopeful that we will see lasting improvements soon.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Thanks for sharing your experience with our Calming Seborrheic Serum, Kimba! We totally understand your desire to avoid prescription chemicals on your daughter's scalp—that's exactly why we created this gentle yet effective alternative! It's great to hear you saw such promising improvement in that first week, and we completely get how it can feel discouraging when progress seems to slow down. What you're experiencing is actually pretty common with seborrheic dermatitis—sometimes the skin goes through cycles as it's healing and adjusting to the treatment. The fact that you're staying consistent with daily application is so important, and we're really hopeful that with continued use you'll start seeing those lasting improvements you're looking for! Thanks for the 4 stars and for giving Dermazen a chance for your daughter! 💚🤩

  • MV
    Melissa V.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Itching, Skin Tone, Flakes
    How old are you? Under 18
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    3 weeks ago
    Amazing!

    Just after using this for a week, my daughter's skin cleared up! I'm so thankful I found this product.

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    Melissa, a whole week and already clear skin? That's absolutely incredible! 🤩 As a parent, there's nothing quite like that feeling of relief when you find something that actually works for your child's skin. We're so thrilled that our Calming Seborrheic Serum delivered such fast results for your daughter!

    It's moments like these that remind us why we do what we do - helping families find real solutions that make a genuine difference. Your daughter's skin is going to love the continued care, and we're just so grateful you gave Dermazen a chance to help. Thank you for this amazing 5-star review and for trusting us with your daughter's skincare needs!💚🙌

  • TR
    Teodora R.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Itching
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    3 weeks ago
    Great product.

    This serum is amazing. It helped with my itching scalp.

    Will order the shampoo too.

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    Oh wow, that's fantastic! 🤩 It sounds like our Calming Seborrheic Serum has really come to the rescue for your scalp, and we couldn't be more thrilled. Here’s to saying goodbye to that pesky itch, and a warm welcome to our shampoo! We can't wait for you to experience the full Dermazen effect. Thanks for giving our serum a try and sharing your experience. 💚😁