Calming Seborrheic Serum












“This calming serum completely cleared up my scalp itching and irritation. More than prescribed creams and ointments from my dermatologist!”
— David Walker
Calming Seborrheic Serum
Dandruff shampoos and moisturizers failed you. Our skin-smart overnight serum works while you sleep, so you wake up with a calmer, flake-free scalp and face. 92% reported less flaking in a 4-week clinical study.*
Reduce flakes
Calm Redness
Soothe Itching
Safe for Malassezia
Reduce flakes
Calm Redness
Soothe Itching
Safe for Malassezia
“This calming serum completely cleared up my scalp itching and irritation. More than prescribed creams and ointments from my dermatologist!”
— David Walker
How It Works
Most scalp and skin care products contain ingredients that can weaken your skin barrier and create buildup that keeps you stuck in the flake cycle. This serum works differently.
-
1Clear the buildup layer
Oil, dead skin, and old product residue keep your flakes coming back, and most products never remove this layer. Now you can. -
2Strengthen your skin, instead of stripping it
While most products can damage your skin and scalp barrier, our serum supports a stronger barrier to prevent flaking and irritation. -
3Get 8+ hours vs. 2 minutes
Most dandruff shampoos rinse off before their job is done. Our serum starts before bed, giving your skin 240x more contact time.
Ingredients
Calming Seborrheic Serum
Water, Sodium Chloride (Sea Salt), Xylitol, Methylsulfonylmethane (MSM), Urea, Niacinamide, Colloidal Silver, Sodium Hyaluronate, Aloe Barbadensis Leaf Juice, Citrus Grandis (Grapefruit) Seed Extract, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Rosemary (Rosmarinus Officinalis) Leaf Oil, Limonene*
*natural allergen from essential oils
Ingredient Highlights
ALOE LEAF JUICE
Aloe barbadensis
Helps soothe and calm signs of visible irritation and moody scalp
UREA
Urea
Boosts hydration and supports a calm, balanced scalp
GRAPEFRUIT SEED EXTRACT
Citrus grandis
Helps to support a calm, clear, balanced scalp
Clean, Barrier-Safe Formulations:
- Barrier Safe All of our formulas are made without ingredients that can feed Malassezia (a common yeast that lives on skin and scalp and is associated with flakes, itching, and breakouts). No oils, fatty acids, or esters that this yeast can eat — anywhere in the routine.
- No Steroids Steroids like hydrocortisone are prescription-style ingredients sometimes used on irritated skin. With long-term use, they’re associated with skin thinning, and stopping them suddenly can lead to rebound flare-ups.
- No Zinc Pyrithione (ZPT) A common anti-dandruff ingredient found in many medicated shampoos. The European Union banned ZPT in cosmetics in March 2024 over concerns about reproductive safety, though it’s still widely used in U.S. products.
- No Coal Tar A leftover byproduct from processing coal, used in some old-school medicated shampoos. Has a strong smell, can stain hair and fabric, and has been flagged by health agencies as a possible cancer risk at higher exposure levels.
- No Selenium Sulfide A medicated ingredient found in some dandruff shampoos. Associated with scalp dryness, irritation, and changes in hair color with regular use.
- No Sulfates Harsh cleansers (like SLS and SLES — the bubbly stuff in many shampoos and body washes). Can strip away natural oils and leave sensitive scalps and skin feeling tight and dry.
- No Parabens A group of preservatives used in tons of personal care products to keep them from spoiling. Studied for acting like estrogen in the body and have been detected in human tissue samples.
- No Phthalates A group of chemicals often hidden inside “fragrance” blends and used to soften plastics. Studied for their effects on hormones and reproductive health.
- No Silicones Synthetic ingredients (look for “-cone” or “-siloxane” on labels) that coat hair to give it temporary slip and shine. Build up over time and can trap dirt and oil against the scalp.
- No PEGs Petroleum-based ingredients (made from the same source as gasoline) used to mix oil and water in many products. Often contaminated during manufacturing with 1,4-dioxane, a chemical of concern flagged by the EPA.
- No Synthetic Fragrance The words “fragrance” or “parfum” on a label can hide dozens of undisclosed chemicals. Among the most commonly reported sources of skin sensitivity in personal care products.
- No Mineral Oil A leftover byproduct from making gasoline, used in many lotions, balms, and hair products. Forms an occlusive layer on skin that can trap dirt against pores.
- No Artificial Dyes Synthetic colorings (the FD&C and D&C numbers you see on labels) added just to make products look pretty. Made from petroleum and associated with skin sensitivity reactions in some people.
- No Talc A soft mineral powder used in some body powders and makeup. Has been the subject of major lawsuits over contamination with asbestos, a regulated mineral fiber classified as a known carcinogen by international health agencies.
- No Triclosan An antibacterial chemical once added to soaps and personal care products everywhere. The FDA banned it from over-the-counter washes in 2016 because companies couldn’t prove it was safe or worked any better than plain soap.
- No BHA/BHT Synthetic preservatives used to keep oils in lotions, lip balms, and cosmetics from going rancid. Studied for their effects on hormones and flagged by some health agencies as ingredients of concern.
- No DEA/TEA Two foam-boosting and pH-balancing chemicals (diethanolamine and triethanolamine) used in many shampoos and cleansers. Can react with other ingredients in the bottle to form nitrosamines — a group of chemicals flagged as a safety concern.
- No EDTA A chemical added to many products to grab onto minerals in tap water and keep formulas stable. Doesn’t break down well in nature and builds up in lakes, rivers, and oceans after it rinses down the drain.
How to Use
- Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.
- The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.
- Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.
- Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.
- Massage in the formula as you thank your body for all its gifts.
- In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.
- Enjoy all-day peaceful skin and peace of mind.
*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.
For Best Results
To further calm your scalp and prevent flakes and irritation, wash with the Scalp Therapy Shampoo.
For your face, first wash with the Purifying Facial Cleanser before applying the serum, then protect your skin's peace with the Soothing Malassezia Moisturizer after the serum.
Stinging Is Possible & Natural
If your skin is highly inflamed, you might experience a stinging sensation, mostly from the sea salt and tea tree essential oil. This is normal.
The aloe and other soothing ingredients will usually calm any discomfort within a minute or two. And as your skin barrier becomes healthier over time, the stinging will become less intense or disappear completely.
If your skin is extra sensitive and the stinging feels unbearable, you can dilute the serum by 50% with purified water and apply it to your skin. The serum is our strongest formula, so there are many folks in the Dermazen community who have seen great results with a diluted serum.
Shipping & Returns
Your order ships fast: we send packages out from Oceanside, CA within 24 business hours (Mon–Sat), with tracking emailed automatically. Standard U.S. delivery is typically 2–5 business days (USPS), and FedEx 2-Day is available if you need it sooner.
Not sure it’s right for your skin? Every U.S. order is backed by our 60-Day Peaceful Skin Guarantee (starting on the day your package is marked delivered). If your skin hasn’t improved, you can return your products for a full refund.
The Key to Calming Your Flaky, Irritated Scalp
Why Moisturizing Will Never Be Enough
Life Changing Results
Customer Testimonials
“The only product that has worked. I got the peaceful skin system bundle after a recent flare up. My skin has made incredible improvements. I’m so grateful I found something that actually works for me.”
Verified Customer
“My skin is clearer than it’s ever been. I am shocked at how well this has worked to clear up the totally entrenched flaking and acne I had across my nose for years. Really nice smelling and feeling.”
Verified Customer
“As close to a miracle as you can get. After years of trying everything to fix my itchy, flaky skin on my face, scalp, and around my nose, these products solved it within days.”
Verified Customer
Why
Dermazen?
We started Dermazen because we lived the struggle personally: visible flakes, redness, blemishes, embarrassment, and products that helped for a week…then stopped working.
So we spent years learning about ingredients and formulations, and took a different approach: formulas made without ingredients known to feed Malassezia, so skin can feel more balanced and comfortable.
Frequently Bought With
Customer Reviews
- PPPaula P.Verified BuyerI recommend this productWhere did you need relief? ScalpWhat did this product help with? Flakes, Itching, Build-UpHow old are you? 35-44What is your gender? FemaleWhat texture is your hair? TexturedRated 5 out of 5 stars1 week agoGreat Product
I only needed to use this product a few times to see dramatic results. In a few weeks, it did what prescription products couldn't do in years.
Was this helpful? - HBHarold B.Verified BuyerI recommend this productWhere did you need relief? ScalpWhat did this product help with? Flakes, ItchingHow old are you? 35-44What is your gender? MaleWhat texture is your hair? CurlyRated 5 out of 5 stars2 weeks agoWent too long trying other products… but only THIS gets it done for me.👍🏿
If you’ve got scalp irritation… DONT think about it, DONT wait, just BUY IT!! 🙌🏿
You’ll thank yourself later… Just remember, consistency is key. (Do the subscription)🙏🏿
Was this helpful? - NKNiharika K.Verified BuyerI recommend this productWhere did you need relief? Body, ScalpWhat did this product help with? Flakes, Itching, Build-UpRated 4 out of 5 stars2 weeks agoLove this product
This was my introduction to Dermazen. This product helped immensely when I first got it and continues to be excellent. I alternate with this serum and the moisturizer
Was this helpful? - BDBrooke D.Verified BuyerI recommend this productWhere did you need relief? ScalpWhat did this product help with? Itching, Skin HealthHow old are you? 45-54What is your gender? FemaleWhat texture is your hair? WavyRated 5 out of 5 stars2 weeks agoInstant soothing
Partnered with the smampoo this stuff is amazing. I put in on right before bed and it instantly soothes my scalp making sleep so much more pleasant. I tried many products before Dermazen with no success. It has been a life saver
Was this helpful? - CWCatreena W.Verified BuyerI recommend this productWhere did you need relief? Scalp, Face, Body, EarsWhat did this product help with? Itching, Skin Health, FlakesHow old are you? 45-54What is your gender? FemaleWhat texture is your hair? OtherRated 5 out of 5 stars2 weeks agoI use this EVERYWHERE
I put it on my scalp a few times a week and sometimes in combination with the scalp moisturizer. The absolute beauty of this one, I put it anywhere I see a dry patch. It clears it right up, sometime overnight and other times a couple of applications. It works miracles. I really wish I had taken before/after pictures of the area under my *******. It was really dry but now it's not. Makes me happy!
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